RWTH Aachen, Department of Experimental Molecular Imaging (ExMI)

Utilize existing synergies, from the preclinical stage to study management. From preclinical to study management. KAIROS’ holistic approach also includes preclinical research. Together with the research partners in the ForSaTum project, a preclinical study information system was developed. This preclinical study information system enables you to cover projects in this area in accordance with the requirements for results orientation, quality and efficiency. A workflow-based study editor not only ensures the best possible documentation, but also the greatest possible standardization of workflows. Both factors, together with the functionalities of CentraXX Meta, make integrated work possible in the first place and help to significantly increase efficiency in research and, in a second step, to improve treatment success. By contrast, development costs decrease significantly.

Efficiency all along the line: Precision begins in the preclinical phase.
The value chain for many further study and treatment steps begins in the preclinical phase. Highest efficiency and optimally usable data therefore set the course for further research and treatment scenarios. In the sense of translational research, CentraXX already starts at this point in order to document the results and allow a continuous flow of information to flow into the following areas such as biobanking and study management and even directly into individual treatment.
Thus, we give you preclinical information systems: our research findings for your success.

In research projects that we conduct jointly with renowned partners, we have established the importance of joint, consolidated data designed for long-term use. In close cooperation with RWTH Aachen University, we developed a study editor in the ForSaTum project (research satellite for the accelerated implementation of new tumour treatment strategies) as a common platform for all those involved in a research project and in multi-center areas of application. Uniform documentation structures and procedural instructions, which are translated from SOPs into executable system workflows, contribute to a uniform end2end process from the first steps of the preclinical project to the analysis and documentation of the results. Of course, the study editor can be used from any location. In the preclinical phase, too, we use an operative link to ensure common structures and standards that significantly increase the informative value and comparability of study results.

Less effort, lower expenditure, with the selective and purposeful deployment of resources.
A major concern of our own efforts is also the lowest possible number of animals used in preclinical care. Their protection is not a side effect, but the declared goal of our work, which is based on the 3Rs principle of Russel and Burch (Replacement, Reducement, Refinement) and is increasingly concentrating on the use of “virtual test animals” and the recycling of data already collected from other studies: Every animal that no longer has to be used in experiments is an important contribution to responsible action.

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